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Sequentially applies all annotation functions to a variant annotation data frame.

Usage

annotate_all_variants(variant_annotation)

Arguments

variant_annotation

A data.frame or tibble containing a column \codeVariants.

Value

The input \codevariant_annotation, with these annotations added in order:

  1. Hypermutable labeling

  2. Population-frequency & haplogroup statistics

  3. Blacklist-region flagging

  4. Homopolymer-region annotation

  5. Amino-acid change & impact via dndscv

  6. Mitochondrial disease associations

  7. Base-change & transition/transversion classification

Examples

if (FALSE) {
df_annot <- annotate_all_variants(my_variant_df)
}